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TUMORS OF THE SMALL INTESTINE
  • duodenum is the commonest site involved
  • most tumors of the duodenum are benign
  • there are various types based on the histology
  • examples are carcinoid tumors, lymphoma, leiomyoma, leiomyosarcomas, adenocarcinomas
  • usual complaints include but are not limited to
    • upper abdominal discomfort
    • "gas" pain
    • nausea
    • vomiting
    • gastrointestinal bleeding
    • anemia
    • significant weight loss
    • food intolerance
    • jaundice

Predisposing Factors:

  • familial polyposis coli
  • Gardner's syndrome
  • Crohn's disease
  • Peutz-Jeghers disease

Treatment:

  • Surgical resection of the tumor is the treatment of choice if the diagnosis is carcinoma.
  • Chemoradiation has been reported to produce complete responses in a few patients using 5-FU based regimens, Mitomycin C and 50 Gy of radiation.
  • Patients with lymphoma are treated with appropriate chemotherapy