- it is a variant of epidermoid carcinoma
associated factors include:
- anal fistula
- male anal receptive intercourse
- human papilloma virus infection
- HIV infection
- treatment is by using combined radiation therapy and chemotherapy (5FU and Mitomycin C)
- in recurrent or resistant cases, radical surgical resection can be performed for salvage.
- prophylactic lymph node resection does not add to the cure rate.